Markus Egner

 

Research Interest

 

Publications

Lewandowski, M.; Granger--Rivière, M.; Mayer, D.; Kasch, T.; Nawa, F.; Egner, M.; Marschner, J.A.; Morozov, V.; Merk, D. Structural Tuning of Partial RXR Agonism and Antagonism. J. Med. Chem., 2025 DOI

Sigal, M.; Egner, M.; Okada, C.; Merk, D.; Sengoku, T.; Katoh, T.; Suga, H. De Novo Discovery of α,α-Disubstituted α-amino Acid-Containing α-helical Peptides as Competitive PPARγ PPI Inhibitors. J. Am. Chem. Soc., 2025 DOI

Egner, M.; Merk, D. Nurr1 modulators - a patent review (2019 - present). Expert Opin. Ther. Pat., 2025 DOI

Egner, M.; Busch, R.; López-García, U.; Lewandowski, M.; Höfner, G.; Wein, T.; Marschner, J. A., Merk, D. A Nurr1 Agonist Derived from the Natural Ligand DHI Induces Neuroprotective Gene Expression. J. Med. Chem., 2025, DOI

Sai, M.; Vietor, J.; Kornmayer, M.; Egner, M.; López-García, U.; Höfner, G.; Pabel, J.; Marschner, J.; Wein, T.; Merk, D. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J. Med. Chem., 2023, DOI